Mayo are into their seventh All-Ireland Senior Football Championship semi-final in-a-row.
Cillian O’Connor, Keith Higgins, Kevin McLoughlin and Andy Moran scored goals as they beat their neighbours Roscommon by 4-19 to 0-9.
Next up for Mayo is a last-four clash with Kerry
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Meanwhile holders Cork will play Galway in the quarter-finals of the All-Ireland Senior Ladies Football Championship.
Eimear Scally and Orla Finn scored five-points each as the got past Monaghan by 0-14 to 1-10 in Tullamore.